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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTGES
All Species:
22.42
Human Site:
S127
Identified Species:
61.67
UniProt:
O14684
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14684
NP_004869.1
152
17102
S127
K
L
R
A
P
I
R
S
V
T
Y
T
L
A
Q
Chimpanzee
Pan troglodytes
XP_528441
152
17073
S127
K
L
R
A
P
I
R
S
V
T
Y
T
L
A
Q
Rhesus Macaque
Macaca mulatta
XP_001107574
152
17098
S127
K
L
R
A
P
I
R
S
V
T
Y
T
L
A
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9JM51
153
17267
S128
K
L
N
P
R
L
R
S
G
A
Y
V
L
A
Q
Rat
Rattus norvegicus
P08011
155
17453
G131
P
L
P
Q
P
N
R
G
L
A
F
F
V
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415475
146
16623
S121
K
L
R
A
P
T
R
S
V
A
Y
S
V
A
Q
Frog
Xenopus laevis
NP_001086699
145
16911
S120
A
L
K
P
P
T
R
S
M
A
Y
S
I
A
Q
Zebra Danio
Brachydanio rerio
NP_001014828
146
16439
S121
A
L
K
A
P
T
R
S
L
A
Y
V
I
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788903
167
18680
A142
P
V
P
Q
P
A
R
A
L
A
F
F
T
T
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
98
N.A.
N.A.
79
36.7
N.A.
N.A.
68.4
60.5
61.1
N.A.
33.5
N.A.
N.A.
N.A.
Protein Similarity:
100
98.6
98.6
N.A.
N.A.
83.6
54.8
N.A.
N.A.
78.2
73
73
N.A.
53.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
53.3
20
N.A.
N.A.
73.3
46.6
53.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
60
40
N.A.
N.A.
86.6
73.3
73.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
0
56
0
12
0
12
0
67
0
0
0
78
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
23
23
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
12
12
0
0
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
34
0
0
0
0
0
0
23
0
0
% I
% Lys:
56
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
89
0
0
0
12
0
0
34
0
0
0
45
0
0
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
12
0
0
0
0
0
0
0
0
0
% N
% Pro:
23
0
23
23
89
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
23
0
0
0
0
0
0
0
0
0
0
78
% Q
% Arg:
0
0
45
0
12
0
100
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
78
0
0
0
23
0
0
0
% S
% Thr:
0
0
0
0
0
34
0
0
0
34
0
34
12
12
0
% T
% Val:
0
12
0
0
0
0
0
0
45
0
0
23
23
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
78
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _